Inverse psoriasis: the diagnostic value of dermatoscopic assessment and the experience of treatment with a combination topical agent (a clinical series)

Background: Inverse psoriasis that is characterized by skinfold rash seen in 12 to 36% of European patients with psoriasis. Isolated involvement skinfolds can mimic a number dermatoses similar location. The differential diagnosis increasingly frequently based on non-invasive methods, including dermatoscopy. Taking into account the warm and wet milieu skinfolds, facilitating secondary infection, topical antibacterials antiseptics are recommended for treatment, along glucocorticosteroids vitamin D3 analogues.
 Materials methods: We have analyzed results assessment treatment 15 major were admitted in-patient department dermatology. All underwent dermatoscopy at 20 magnification. treated desensitizing agents, hepatic protectors, group B vitamins. Topical treatments applied areas included combination agent containing mometasone furoate (0.5 mg), gentamicin sulfate (1 econazole nitrate (10 dexpanthenol (50 mg). was considered effective if M-PASI decreased least 75%; assessed after 7 14 days treatment.
 Results: In all cases, vulgar lesions showed vermilion or red rosy background evenly distributed dotted vessels white scales diffusely located over visualized surface. vessels, either as isolated groups, periphery areas; some plaques had local erosions, one case, hemorrhages. Morphological biopsy samples (n = 5) confirmed Treatment-induced improvement day 2 3, 14, there decrease 90% 6 (40%) resolution 9 (60%). There no treatment-associated adverse events reactions.
 Conclusion: Dermatoscopy has proved be useful tool diagnostics inverse At low magnification ( 20), its main sign an even distribution throughout area. dermatoscopic symptoms additionally grouped foci. addition (mometasone furoate, sulfate, nitrate, dexpanthenol) standard systemic therapy facilitated almost full psoriatic lesions.